Mitochondries, métaux et stress oxydatif>> Publications

Publications 2018

Impaired Transferrin Receptor Palmitoylation and Recycling in Neurodegeneration with Brain Iron Accumulation.
Drecourt A, Babdor J, Dussiot M, Petit F, Goudin N, Garfa-Traoré M, Habarou F, Bole-Feysot C, Nitschké P, Ottolenghi C, Metodiev MD, Serre V, Desguerre I, Boddaert N, Hermine O, Munnich A, Rötig A.
Am J Hum Genet. 2018 Feb 1;102(2):266-277.

Quantitative proteomics in Friedreich's ataxia B-lymphocytes: A valuable approach to decipher the biochemical events responsible for pathogenesis.
Télot L, Rousseau E, Lesuisse E, Garcia C, Morlet B, Léger T, Camadro JM, Serre V.
Biochim Biophys Acta. 2018 Jan 9;1864(4 Pt A):997-1009.

Publications 2017

Modulation of the specific glutathionylation of mitochondrial proteins in the yeast Saccharomyces cerevisiae under basal and stress conditions.
Gergondey R, Garcia C, Marchand C, Lemaire S, Camadro JM, Auchere F.
Biochem J. 2017 Feb 6. pii: BCJ20160927.

Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy.
Ait-El-Mkadem S, Dayem-Quere M, Gusic M, Chaussenot A, Bannwarth S, François B, Genin EC, Fragaki K, Volker-Touw CL, Vasnier C, Serre V, van Gassen KL, Lespinasse F, Richter S, Eisenhofer G, Rouzier C, Mochel F, De Saint-Martin A, Abi Warde MT, de Sain-van der Velde MG, Jans JJ, Amiel J, Avsec Z, Mertes C, Haack TB, Strom T, Meitinger T, Bonnen PE, Taylor RW, Gagneur J, van Hasselt PM, Rötig A, Delahodde A, Prokisch H, Fuchs SA, Paquis-Flucklinger V.
Am J Hum Genet. 2017 Jan 5;100(1):151-159.

Publications 2016

Compound heterozygosity for severe and hypomorphic NDUFS2 mutations cause non-syndromic LHON-like optic neuropathy.
Gerber S, Ding MG, Gérard X, Zwicker K, Zanlonghi X, Rio M, Serre V, Hanein S, Munnich A, Rotig A, Bianchi L, Amati-Bonneau P, Elpeleg O, Kaplan J, Brandt U, Rozet JM. 
J Med Genet. 2016 Dec 28. pii: jmedgenet-2016-104212.

Insights into Brain Glycogen Metabolism: The Structure of Human Brain Glycogen Phosphorylase.
Mathieu C, Li de la Sierra-Gallay I, Duval R, Xu X, Cocaign A, Léger T, Woffendin G, Camadro JM, Etchebest C, Haouz A, Dupret JM, Rodrigues-Lima F.
J Biol Chem. 2016 Aug 26;291(35):18072-83.

The metacaspase Mca1p restricts O-glycosylation during farnesol-induced apoptosis in Candida albicans.
Léger T, Garcia C, Camadro JM.
Mol Cell Proteomics. 2016 Apr 28.

Ostreococcus tauri is a new model green alga for studying iron metabolism in eukaryotic phytoplankton.
Lelandais G, Scheiber I, Paz-Yepes J, Lozano JC, Botebol H, Pilátová J, Žárský V, Léger T, Blaiseau PL, Bowler C, Bouget FY, Camadro JM, Sutak R, Lesuisse E.
BMC Genomics. 2016 May 3;17(1):319.

A Network of Paralogous Stress Response Transcription Factors in the Human Pathogen Candida glabrata.
Merhej J, Thiebaut A, Blugeon C, Pouch J, Ali Chaouche Mel A, Camadro JM, Le Crom S, Lelandais G, Devaux F.
Front Microbiol. 2016 May 9;7:645. eCollection 2016.

The adaptive metabolic response involves specific protein glutathionylation during the filamentation process in the pathogen Candida albicans.
Gergondey R, Garcia C, Serre V, Camadro JM, Auchère F.
Biochim Biophys Acta. 2016 Apr 12.

ChIPseq in Yeast Species: From Chromatin Immunoprecipitation to High-Throughput Sequencing and Bioinformatics Data Analyses.
Lelandais G, Blugeon C, Merhej J.
Methods Mol Biol. 2016;1361:185-202.

Label-Free Quantitative Proteomics in Yeast.
Léger T, Garcia C, Videlier M, Camadro JM.
Methods Mol Biol. 2016;1361:289-307.

Publications 2015

Central role for ferritin in the day/night regulation of iron homeostasis in marine phytoplankton.
Botebol H, Lesuisse E, Šuták R, Six C, Lozano JC, Schatt P, Vergé V, Kirilovsky A, Morrissey J, Léger T, Camadro JM, Gueneugues A, Bowler C, Blain S, Bouget FY.
Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14652-7. Epub 2015 Nov 9.

A Yeast/Drosophila Screen to Identify New Compounds Overcoming Frataxin Deficiency.
Seguin A, Monnier V, Palandri A, Bihel F, Rera M, Schmitt M, Camadro JM, Tricoire H, Lesuisse E.
Oxid Med Cell Longev. 2015;2015:565140. Epub 2015 Oct 11.

Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies.
Rouillon J, Poupiot J, Zocevic A, Amor F, Léger T, Garcia C, Camadro JM, Wong B, Pinilla R, Cosette J, Coenen-Stass AM, Mcclorey G, Roberts TC, Wood MJ, Servais L, Udd B, Voit T, Richard I, Svinartchouk F.
Hum Mol Genet. 2015 Sep 1;24(17):4916-32. Epub 2015 Jun 9.

Fermentation and Alternative Respiration Compensate for NADH Dehydrogenase Deficiency in a Prokaryotic Model of DJ-1 Associated Parkinsonism.
Messaoudi N, Gautier V, Dairou J, Mihoub M, Lelandais G, Bouloc P, Landoulsi A, Richarme G.
Microbiology. 2015 Sep 15.

Yap7 is a transcriptional repressor of nitric oxide oxidase in yeasts, which arose from neofunctionalization after whole genome duplication.
Merhej J, Delaveau T, Guitard J, Palancade B, Hennequin C, Garcia M, Lelandais G, Devaux F.
Mol Microbiol. 2015 Jun;96(5):951-72. Epub 2015 Mar 28.

Identification of a novel ARL13B variant in a Joubert syndrome-affected patient with retinal impairment and obesity.
Thomas S, Cantagrel V, Mariani L, Serre V, Lee JE, Elkhartoufi N, de Lonlay P, Desguerre I, Munnich A, Boddaert N, Lyonnet S, Vekemans M, Lisgo SN, Caspary T, Gleeson J, Attié-Bitach T.
Eur J Hum Genet. 2015 May;23(5):621-7. Epub 2014 Aug 20.

A novel protein, ubiquitous in marine phytoplankton, concentrates iron at the cell surface and facilitates uptake.
Morrissey J, Sutak R, Paz-Yepes J, Tanaka A, Moustafa A, Veluchamy A, Thomas Y, Botebol H, Bouget FY, McQuaid JB, Tirichine L, Allen AE, Lesuisse E, Bowler C.
Curr Biol. 2015 Feb 2;25(3):364-71. Epub 2014 Dec 31.

The metacaspase (Mca1p) has a dual role in farnesol-induced apoptosis in Candida albicans.
Léger T, Garcia C, Ounissi M, Lelandais G, Camadro JM.
Mol Cell Proteomics. 2015 Jan;14(1):93-108. Epub 2014 Oct 27.

Publications 2014

Progression from cirrhosis to cancer is associated with early ubiquitin post-translational modifications: identification of new biomarkers of cirrhosis at risk of malignancy.
Laouirem S, Le Faouder J, Alexandrov T, Mestivier D, Léger T, Baudin X, Mebarki M, Paradis V, Camadro JM, Bedossa P.
J Pathol. 2014 Dec;234(4):452-63. Epub 2014 Sep 12.

Screening of CHCHD10 in a French cohort confirms the involvement of this gene in frontotemporal dementia with amyotrophic lateral sclerosis patients.
Chaussenot A, Le Ber I, Ait-El-Mkadem S, Camuzat A, de Septenville A, Bannwarth S, Genin EC, Serre V, Augé G; French research network on FTD and FTD-ALS, Brice A, Pouget J, Paquis-Flucklinger V.
Neurobiol Aging. 2014 Dec;35(12):2884.e1-4. Epub 2014 Jul 24.

A thermolabile aldolase A mutant causes fever-induced recurrent rhabdomyolysis without hemolytic anemia.
Mamoune A, Bahuau M, Hamel Y, Serre V, Pelosi M, Habarou F, Nguyen Morel MA, Boisson B, Vergnaud S, Viou MT, Nonnenmacher L, Piraud M, Nusbaum P, Vamecq J, Romero N, Ottolenghi C, Casanova JL, de Lonlay P.
PLoS Genet. 2014 Nov 13;10(11):e1004711. eCollection 2014 Nov.

bPeaks: a bioinformatics tool to detect transcription factor binding sites from ChIPseq data in yeasts and other organisms with small genomes.
Merhej J, Frigo A, Le Crom S, Camadro JM, Devaux F, Lelandais G.
Yeast. 2014 Oct;31(10):375-91. Epub 2014 Jul 28.

Changes in glutathione-dependent redox status and mitochondrial energetic strategies are part of the adaptive response during the filamentation process in Candida albicans.
Guedouari H, Gergondey R, Bourdais A, Vanparis O, Bulteau AL, Camadro JM, Auchère F.
Biochim Biophys Acta. 2014 Sep;1842(9):1855-69. Epub 2014 Jul 10.

A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement.
Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore DG, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V.
Brain. 2014 Aug;137(Pt 8):2329-45. Epub 2014 Jun 16.

Proteomics profiling of urine reveals specific titin fragments as biomarkers of Duchenne muscular dystrophy.
Rouillon J, Zocevic A, Leger T, Garcia C, Camadro JM, Udd B, Wong B, Servais L, Voit T, Svinartchouk F.
Neuromuscul Disord. 2014 Jul;24(7):563-73. doi: . Epub 2014 Apr 13.

Tissue- and cell-specific mitochondrial defect in Parkin-deficient mice.
Damiano M, Gautier CA, Bulteau AL, Ferrando-Miguel R, Gouarne C, Paoli MG, Pruss R, Auchère F, L'Hermitte-Stead C, Bouillaud F, Brice A, Corti O, Lombès A.
PLoS One. 2014 Jun 24;9(6):e99898. eCollection 2014.

Efficient gene targeting and removal of foreign DNA by homologous recombination in the picoeukaryote Ostreococcus.
Lozano JC, Schatt P, Botebol H, Vergé V, Lesuisse E, Blain S, Carré IA, Bouget FY.
Plant J. 2014 Jun;78(6):1073-83. Epub 2014 May 23.

Quantitative multiplex PCR of short fluorescent fragments for the detection of large intragenic POLG rearrangements in a large French cohort.
Rouzier C, Chaussenot A, Serre V, Fragaki K, Bannwarth S, Ait-El-Mkadem S, Attarian S, Kaphan E, Cano A, Delmont E, Sacconi S, Mousson de Camaret B, Rio M, Lebre AS, Jardel C, Deschamps R, Richelme C, Pouget J, Chabrol B, Paquis-Flucklinger V.
Eur J Hum Genet. 2014 Apr;22(4):542-50. Epub 2013 Aug 7.

In situ proteomic analysis by MALDI imaging identifies ubiquitin and thymosin-β4 as markers of malignant intraductal pancreatic mucinous neoplasms.
Rebours V, Le Faouder J, Laouirem S, Mebarki M, Albuquerque M, Camadro JM, Léger T, Ruszniewski P, Lévy P, Paradis V, Bedossa P, Couvelard A.
Pancreatology. 2014 Mar-Apr;14(2):117-24. Epub 2013 Dec 17.

Giardia intestinalis incorporates heme into cytosolic cytochrome b₅.
Pyrih J, Harant K, Martincová E, Sutak R, Lesuisse E, Hrdý I, Tachezy J.
Eukaryot Cell. 2014 Feb;13(2):231-9. Epub 2013 Dec 2.

Different iron sources to study the physiology and biochemistry of iron metabolism in marine micro-algae.
Botebol H, Sutak R, Scheiber IF, Blaiseau PL, Bouget FY, Camadro JM, Lesuisse E.
Biometals. 2014 Feb;27(1):75-88. Epub 2013 Nov 27.

The basis for evolution of DNA-binding specificity of the Aft1 transcription factor in yeasts.
Gonçalves IR, Conde e Silva N, Garay CL, Lesuisse E, Camadro JM, Blaiseau PL.
Genetics. 2014 Jan;196(1):149-60. Epub 2013 Oct 30.

Methylene blue rescues heart defects in a Drosophila model of Friedreich's ataxia.
Tricoire H, Palandri A, Bourdais A, Camadro JM, Monnier V.
Hum Mol Genet. 2014 Feb 15;23(4):968-79. Epub 2013 Oct 8.

Publications 2013

Interaction between methionine synthase isoforms and MMACHC: characterization in cblG-variant, cblG and cblC inherited causes of megaloblastic anaemia.
Fofou-Caillierez MB, Mrabet NT, Chéry C, Dreumont N, Flayac J, Pupavac M, Paoli J, Alberto JM, Coelho D, Camadro JM, Feillet F, Watkins D, Fowler B, Rosenblatt DS, Guéant JL.
Hum Mol Genet. 2013 Nov 15;22(22):4591-601.Epub 2013 Jul 3.

Imaging mass spectrometry reveals modified forms of histone H4 as new biomarkers of microvascular invasion in hepatocellular carcinomas.
Poté N, Alexandrov T, Le Faouder J, Laouirem S, Léger T, Mebarki M, Belghiti J, Camadro JM, Bedossa P, Paradis V.
Hepatology. 2013 Sep;58(3):983-94. Epub 2013 Jul 30.

Global stress response in a prokaryotic model of DJ-1-associated Parkinsonism.
Messaoudi N, Gautier V, Kthiri F, Lelandais G, Mihoub M, Joseleau-Petit D, Caldas T, Bohn C, Tolosa L, Rao G, Tao K, Landoulsi A, Bouloc P, Richarme G.
J Bacteriol. 2013 Mar;195(6):1167-78. . Epub 2013 Jan 4.

Publications 2012

Apn1 AP-endonuclease is essential for the repair of oxidatively damaged DNA bases in yeast frataxin-deficient cells.
Lefevre S, Brossas C, Auchère F, Boggetto N, Camadro JM, Santos R.
Hum Mol Genet. 2012 Jun 16. [Epub ahead of print]
PubMed PMID: 22706278.
Homocysteinylation of neuronal proteins contributes to folate deficiency-associated alterations of differentiation, vesicular transport and plasticity in hippocampal neuronal cells
Akchiche N, Bossenmeyer-Pourié C, Kerek R, Martin N, Pourié G, Koziel V, Helle D, Alberto JM, Ortiou S, Camadro JM, Léger T, Guéant JL, Daval JL
FASEB J. 2012 published ahead of print June 19, 2012
Human mitochondrial ferritin improves respiratory function in yeast mutants deficient in iron–sulfur cluster biogenesis, but is not a functional homologue of yeast frataxin
Sutak R, Seguin A, Garcia-Serres R, Oddou JL, Dancis A, Tachezy J, Latour JM, Camadro JM, Lesuisse E.
MicrobiologyOpen. 2012 March 27; 1(2): 95-104

Oxidative stress induces mitochondrial fragmentation in frataxin-deficient cells.
Lefevre S, Sliwa D, Rustin P, Camadro JM, Santos R.
Biochem Biophys Res Commun. 2012 Feb 10;418(2):336-41. Epub 2012 Jan 17.
PMID: 22274609

Changes in mitochondrial glutathione levels and protein thiol oxidation in ∆yfh1 yeast cells and the lymphoblasts of patients with Friedreich's ataxia.
Bulteau AL, Planamente S, Jornea L, Dur A, Lesuisse E, Camadro JM, Auchère F.
Biochim Biophys Acta. 2012 Feb;1822(2):212-25. Epub 2011 Nov 11.
PMID: 22200491

The yeast metacaspase is implicated in oxidative stress response in frataxin-deficient cells.
Lefevre S, Sliwa D, Auchère F, Brossas C, Ruckenstuhl C, Boggetto N, Lesuisse E, Madeo F, Camadro JM, Santos R.
FEBS Lett. 2012 Jan 20;586(2):143-8. Epub 2011 Dec 7.
PMID: 22155640

Inactivation of mitochondrial aspartate aminotransferase contributes to the respiratory deficit of yeast frataxin-deficient cells.
Sliwa D, Dairou J, Camadro JM, Santos R.
Biochem J. 2012 Feb 1;441(3):945-53.
PMID: 22010850

Comparative electrochemical study of superoxide reductases.
Cordas CM, Raleiras P, Auchère F, Moura I, Moura JJ.
Eur Biophys J. 2012 Feb;41(2):209-15. Epub 2011 Dec 6.
PMID: 22143105

Mutation in the Fe-S scaffold protein Isu bypasses frataxin deletion.
Yoon H, Golla R, Lesuisse E, Pain J, Donald JE, Lyver ER, Pain D, Dancis A.
Biochem J. 2012 Jan 1;441(1):473-80.
PMID: 21936771

Publications 2011

Proteomic analysis of virus-host interactions in an infectious context using recombinant viruses.
Komarova AV, Combredet C, Meyniel-Schicklin L, Chapelle M, Caignard G, Camadro JM, Lotteau V, Vidalain PO, Tangy F.
Mol Cell Proteomics. 2011 Dec;10(12):M110.007443. Epub 2011 Sep 12.
PMID: 21911578


Rim2, a pyrimidine nucleotide exchanger, is needed for iron utilization in mitochondria.
Yoon H, Zhang Y, Pain J, Lyver ER, Lesuisse E, Pain D, Dancis A.
Biochem J. 2011 Nov 15;440(1):137-46.
PMID: 21777202

Friedreich's ataxia: the vicious circle hypothesis revisited.
Bayot A, Santos R, Camadro JM, Rustin P.
BMC Med. 2011 Oct 11;9:112.
PMID: 21985033

2-thioxanthines are mechanism-based inactivators of myeloperoxidase that block oxidative stress during inflammation.
Tidén AK, Sjögren T, Svensson M, Bernlind A, Senthilmohan R, Auchère F, Norman H, Markgren PO, Gustavsson S, Schmidt S, Lundquist S, Forbes LV, Magon NJ, Paton LN, Jameson GN, Eriksson H, Kettle AJ.
J Biol Chem. 2011 Oct 28;286(43):37578-89. Epub 2011 Aug 31.
PMID: 21880720

Imaging mass spectrometry provides fingerprints for distinguishing hepatocellular carcinoma from cirrhosis.
Le Faouder J, Laouirem S, Chapelle M, Albuquerque M, Belghiti J, Degos F, Paradis V, Camadro JM, Bedossa P.
J Proteome Res. 2011 Aug 5;10(8):3755-65. Epub 2011 Jul 1.
PMID: 21675781

Gex1 is a yeast glutathione exchanger that interferes with pH and redox homeostasis.
Dhaoui M, Auchère F, Blaiseau PL, Lesuisse E, Landoulsi A, Camadro JM, Haguenauer-Tsapis R, Belgareh-Touzé N.
Mol Biol Cell. 2011 Jun 15;22(12):2054-67. doi: 10.1091/mbc.E10-11-0906. Epub 2011 Apr 13.
PMID: 21490148

A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress.
Achcar F, Camadro JM, Mestivier D.
BMC Syst Biol. 2011 Apr 13;5:51.
PMID: 21489274

Co-precipitation of phosphate and iron limits mitochondrial phosphate availability in Saccharomyces cerevisiae lacking the yeast frataxin homologue (YFH1).
Seguin A, Santos R, Pain D, Dancis A, Camadro JM, Lesuisse E.
J Biol Chem. 2011 Feb 25;286(8):6071-9. Epub 2010 Dec 28.
PMID: 21189251

Publications 2010

Nonreductive iron uptake mechanism in the marine alveolate Chromera velia.
Sutak R, Slapeta J, San Roman M, Camadro JM, Lesuisse E.
Plant Physiol. 2010 Oct;154(2):991-1000. Epub 2010 Aug 19.
PMID: 20724644

Evidence that yeast frataxin is not an iron storage protein in vivo.
Seguin A, Sutak R, Bulteau AL, Garcia-Serres R, Oddou JL, Lefevre S, Santos R, Dancis A, Camadro JM, Latour JM, Lesuisse E.
Biochim Biophys Acta. 2010 Jun;1802(6):531-8. Epub 2010 Mar 20.
PMID: 20307653

Frataxin and mitochondrial FeS cluster biogenesis.
Stemmler TL, Lesuisse E, Pain D, Dancis A.
J Biol Chem. 2010 Aug 27;285(35):26737-43. Epub 2010 Jun 3. Review.
PMID: 20522547

Friedreich's Ataxia: Molecular mechanisms, redox considerations and therapeutic opportunities
Santos R, Lefevre S, Sliwa D, Seguin A, Camadro JM, Lesuisse E.
Antioxid Redox Signal. 2010 Feb 16. [Epub ahead of print]. Review.
PMID: 20156111

Publications 2009

The monothiol single-domain glutaredoxin is conserved in the highly reduced mitochondria of Giardia intestinalis.
Rada P, Smíd O, Sutak R, Dolezal P, Pyrih J, Zársky V, Montagne JJ, Hrdy I, Camadro JM, Tachezy J.
Eukaryot Cell. 2009 Oct;8(10):1584-91.
PMID: 19717741

Determination with matrix-assisted laser desorption/ionization tandem time-of-flight mass spectrometry of the extensive disulfide bonding in tarantula venom peptide Psalmopeotoxin I.
Combes A, Choi SJ, Pimentel C, Darbon H, Waidelich D, Mestivier D, Camadro JM.
Eur J Mass Spectrom (Chichester, Eng). 2009;15(4):517-29.
PMID: 19661560

KlAft, the Kluyveromyces lactis ortholog of Aft1 and Aft2, mediates activation of iron-responsive transcription through the PuCACCC Aft-type sequence.
Conde e Silva N, Gonçalves IR, Lemaire M, Lesuisse E, Camadro JM, Blaiseau PL.
Genetics. 2009 Sep;183(1):93-106.
PMID: 19581449

The antifungal plant defensin RsAFP2 from radish induces apoptosis in a metacaspase independent way in Candida albicans.
Aerts AM, Carmona-Gutierrez D, Lefevre S, Govaert G, François IE, Madeo F, Santos R, Cammue BP, Thevissen K.
FEBS Lett. 2009 Aug 6;583(15):2513-6.
PMID: 19596007

AutoClass@IJM: a powerful tool for Bayesian classification of heterogeneous data in biology.
Achcar F, Camadro JM, Mestivier D.
Nucleic Acids Res. 2009 Jul 1;37(Web Server issue):W63-7.
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Overexpression of the yeast frataxin homolog (Yfh1): contrasting effects on iron-sulfur cluster assembly, heme synthesis and resistance to oxidative stress.
Seguin A, Bayot A, Dancis A, Rogowska-Wrzesinska A, Auchère F, Camadro JM, Bulteau AL, Lesuisse E.
Mitochondrion. 2009 Apr;9(2):130-8.
PMID: 19460301

Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia.
Paupe V, Dassa EP, Goncalves S, Auchère F, Lönn M, Holmgren A, Rustin P.
PLoS One. 2009;4(1):e4253.
PMID: 19158945

Publications 2008

Glutathione-dependent redox status of frataxin-deficient cells in a yeast model of Friedreich's ataxia.
Auchère F, Santos R, Planamente S, Lesuisse E, Camadro JM.
Hum Mol Genet. 2008 Sep 15;17(18):2790-802. Epub 2008 Jun 18.
PMID: 18562474

Substrate- and ubiquitin-dependent trafficking of the yeast siderophore transporter Sit1.
Erpapazoglou Z, Froissard M, Nondier I, Lesuisse E, Haguenauer-Tsapis R, Belgareh-Touzé N.
Traffic. 2008 Aug;9(8):1372-91.
PMID: 18489705

Crusade for iron: iron uptake in unicellular eukaryotes and its significance for virulence.
Sutak R, Lesuisse E, Tachezy J, Richardson DR.
Trends Microbiol. 2008 Jun;16(6):261-8. Review.
PMID: 18467097

Publications 2007

Trafficking of siderophore transporters in Saccharomyces cerevisiae and intracellular fate of ferrioxamine B conjugates.
Froissard M, Belgareh-Touzé N, Dias M, Buisson N, Camadro JM, Haguenauer-Tsapis R, Lesuisse E.
Traffic. 2007 Nov;8(11):1601-16.
PMID: 17714436

Frataxin, a conserved mitochondrial protein, in the hydrogenosome of Trichomonas vaginalis.
Dolezal P, Dancis A, Lesuisse E, Sutak R, Hrd_ I, Embley TM, Tachezy J.
Eukaryot Cell. 2007 Aug;6(8):1431-8.
PMID: 17573543

Oxidative stress and protease dysfunction in the yeast model of Friedreich ataxia.
Bulteau AL, Dancis A, Gareil M, Montagne JJ, Camadro JM, Lesuisse E.
Free Radic Biol Med. 2007 May 15;42(10):1561-70.
PMID: 17448903

Publications 2006

Solution structure of PcFK1, a spider peptide active against Plasmodium falciparum.
Pimentel C, Choi SJ, Chagot B, Guette C, Camadro JM, Darbon H.
Protein Sci. 2006 Mar;15(3):628-34.
PMID: 16452619

GTP in the mitochondrial matrix plays a crucial role in organellar iron homoeostasis.
Gordon DM, Lyver ER, Lesuisse E, Dancis A, Pain D.
Biochem J. 2006 Nov 15;400(1):163-8.
PMID: 16842238

Mrs3p, Mrs4p, and frataxin provide iron for Fe-S cluster synthesis in mitochondria.
Zhang Y, Lyver ER, Knight SA, Pain D, Lesuisse E, Dancis A.
J Biol Chem. 2006 Aug 11;281(32):22493-502.
PMID: 16769722

Publications 2005

Mutations in human CPO gene predict clinical expression of either hepatic hereditary coproporphyria or erythropoietic harderoporphyria.
Schmitt C, Gouya L, Malonova E, Lamoril J, Camadro JM, Flamme M, Rose C, Lyoumi S, Da Silva V, Boileau C, Grandchamp B, Beaumont C, Deybach JC, Puy H.
Hum Mol Genet. 2005 Oct 15;14(20):3089-98
PMID: 16159891

Iron acquisition from transferrin by Candida albicans depends on the reductive pathway.
Knight SA, Vilaire G, Lesuisse E, Dancis A.
Infect Immun. 2005 Sep;73(9):5482-92.
PMID: 16113264

Courel M, Lallet S, Camadro JM, Blaiseau PL.
Direct Activation of Genes Involved in Intracellular Iron Use by the Yeast Iron-Responsive Transcription Factor Aft2 without Its Paralog Aft1.
Mol Cell Biol . 2005 Aug;25(15):6760-71.
PMID: 16024809

Rao AU, Carta LK, Lesuisse E, Hamza I.
Lack of heme synthesis in a free-living eukaryote.
Proc Natl Acad Sci U S A
. 2005 Mar 22;102(12):4270-5
PMID: 15767563

Ouchetto H, Dias M, Mornet R, Lesuisse E, Camadro JM.
A new route to trihydroxamate-containing artificial siderophores and synthesis of a new fluorescent probe.
Bioorg Med Chem . 2005 Mar 1;13(5):1799-803.
PMID: 15698797

Zhang Y, Lyver ER,Knight SA, Lesuisse E, Dancis A.
Frataxin and mitochondrial carrier proteins, Mrs3p and Mrs4p, cooperate in providing iron for heme synthesis.
J Biol Chem. 2005 May 20;280(20):19794-807
PMID: 15767258

Lesuisse E, Knight SA, Courel M, Santos R, Camadro JM, Dancis A.
Genome-wide screen for genes with effects on distinct iron uptake activities in Saccharomyces cerevisiae.
Genetics. 2005 Jan;169(1):107-22. Epub 2004 Oct 16.
PMID: 15489514

Publications 2004

Siderophore and haem iron use by Tritrichomonas foetus.
Sutak R, Chamot C, Tachezy J, Camadro JM, Lesuisse E.
Microbiology. 2004 Dec;150(Pt 12):3979-87.
PMID: 15583151

Santos R, Buisson N, Knight SA, Dancis A, Camadro JM, Lesuisse E.
Candida albicans lacking the frataxin homologue: a relevant yeast model for studying the role of frataxin.
Mol Microbiol. 2004 Oct;54(2):507-19.
PMID: 15469520

Choi SJ, Parent R, Guillaume C, Deregnaucourt C, Delarbre C, Ojcius DM, Montagne JJ, Celerier ML, Phelipot A, Amiche M, Molgo J, Camadro JM, Guette C.
Isolation and characterization of Psalmopeotoxin I and II: two novel antimalarial peptides from the venom of the tarantula Psalmopoeus cambridgei.
FEBS Lett. 2004 Aug 13;572(1-3):109-17.
PMID: 15304333

Sutak R, Chamot C, Tachezy J, Camadro JM, Lesuisse E.
Siderophore and haem iron use by Tritrichomonas foetus.
Microbiology. 2004 Dec;150(Pt 12):3979-87.
PMID: 15583151

He Y, Alam SL, Proteasa SV, Zhang Y, Lesuisse E, Dancis A, Stemmler TL.
Yeast frataxin solution structure, iron binding, and ferrochelatase interaction.
Biochemistry. 2004 Dec 28;43(51):16254-62.
PMID: 15610019

Selmane T, Camadro JM, Conilleau S, Fleury F, Tran V, Prevost C, Takahashi M.
Identification of the subunit-subunit interface of Xenopus Rad51.1 protein: similarity to RecA.
J Mol Biol . 2004 Jan 23;335(4):895-904.
PMID: 14698287

Lesuisse E, Lyver ER, Knight SA, Dancis A.
Role of YHM1, encoding a mitochondrial carrier protein, in iron distribution of yeast.
Biochem J.

2004 Mar 1;378(Pt 2):599-607.
PMID: 14629196 [PubMed - indexed for MEDLINE]

Publications 2003

Santos R, Dancis A, Eide D, Camadro JM, Lesuisse E.
Zinc suppresses the iron-accumulation phenotype of Saccharomyces cerevisiae lacking the yeast frataxin homologue (Yfh1).
Biochem J. 2003 Oct 15;375(Pt 2):247-54.
PMID: 12868958

Guegan R, Camadro JM, Saint Girons I, Picardeau M
Leptospira spp. possess a complete haem biosynthetic pathway and are able to use exogenous haem sources.
Mol Microbiol. 2003 Aug;49(3):745-54.
PMID: 12864856

Graciet E, Gans P, Wedel N, Lebreton S, Camadro JM, Gontero B.
The small protein CP12: a protein linker for supramolecular complex assembly.
Biochemistry . 2003 Jul 15;42(27):8163-70.
PMID: 12846565

Lesuisse E, Santos R, Matzanke BF, Knight SA, Camadro JM, Dancis A.
Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1).
Hum Mol Genet. 2003 Apr 15;12(8):879-89.
PMID: 12668611

Santos R, Buisson N, Knight S, Dancis A, Camadro JM, Lesuisse E.
Haemin uptake and use as an iron source by Candida albicans: role of CaHMX1-encoded haem oxygenase.
Microbiology. 2003 Mar;149(Pt 3):579-88.
PMID: 12634327

Publications 2001

Blaiseau PL, Lesuisse E, Camadro JM.
Aft2p, a novel iron-regulated transcription activator that modulates, with Aft1p, intracellular iron use and resistance to oxidative stress in yeast.
J Biol Chem. 2001 Sep 7;276(36):34221-6. 

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