Molecular and Cellular Pathology Program

Program Leader: Jean-Michel Camadro

Secretariat: Mireille Guillard

“Molecular and Cellular Pathology” is a research program that groups teams who are working to develop new theoretical and/or practical approaches to gain a better understanding of the molecular and cellular bases of rare diseases (genetic diseases) and more common affections (cancer, diseases of reproduction, autoimmune diseases etc.). The teams that are part of this program at the interface between biology and medicine make use of the tools provided by molecular genetics, cell biology, transgenesis and animal models, genomics and bioinformatics, and they benefit from the scientific and technical resources to be found at the Institut Jacques Monod, and in particular its core facilities. 



The themes currently under study concern the role of DNA replication errors in cancer development, the mechanisms of tumor progression and of human genetic diseases affecting normal mitochondrial function, responses to oxidative stress, cell differentiation and embryonic development or ovarian function, the pathological implication of inflammation at the fetal/maternal interface or in autoimmune syndromes.
Particular emphasis is placed on developing methods for modeling normal and pathological complex biological processes. 

These studies are conducted on various biological systems: animal models (mouse), human tissues or cell lines, yeast, plants.

Research teams in the Molecular and Cellular Pathology Program:


See the organizational chart of the Institut Jacques-Monod.

Last modified 01/16/2012

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