Genomes and Epigenomes Program
Program Leader: Térence Strick
Secretariat: Stéphane Hoyez
The Program in Genomes and Epigenomes brings together research teams interested in the regulation of DNA and protein metabolism. This includes fundamental processes of genome maintenance such as the control of DNA replication and damage repair; transcriptional regulation; nucleo-cytoplasmic trafficking and the regulation of cellular trafficking by ubiquitylation; and protein processing, folding and export.
Research models include bacteria and eukaryotes such as yeast, chicken and human cell lines. In addition, a range of advanced methodologies are represented in the Program, including real-time single-molecule imaging and manipulation and high-density microarray analysis of gene replication and transcription. These efforts are supported by the Genomics Platform and the Protein Purification Platform.
Research groups in the Genomes and Epigenomes Program:
- Ubiquitin and Dynamics of Molecular Scaffolds (Catherine Dargemont)
- Epigenetic Regulation of Genome Organization (Sandra Duharcourt)
- Epigenome and Paleogenome (Thierry Grange et Eva-Maria Geigl)
- Chromosomal Domains and Replication (Marie-Noëlle Prioleau)
- Stress Molecules (Gilbert Richarme)
- Single Molecule Nanomanipulation (Térence Strick)
See the Organizational Chart of the Institut Jacques-Monod.
Last modified 01/18/2012