Cell Biology Program
Program Leader: Valérie Doye
Secretariat: Véra Guez
The overall goal of the research groups in the Cell Biology Program is to understand the fundamental processes contributing to the structure, dynamics and functions of eukaryotic cells. We study different cellular components (nuclei, transport vesicles, mitochondria, cytoskeleton etc), their assembly, regulation, signaling pathways and their roles in determining cell shape, motility, proliferation, tissue organisation and development, in both normal and pathological conditions.
Current research themes include the transport of macromolecules, membrane flux, responses to external molecular or mechanical stimuli, the role of posttranslational modifications in protein function and targeting, and the processes contributing to the maintenance of cell integrity (both cytoplasmic and genomic) during cell division.
The strength of the Program lies in the quality of the research groups, the diversity of model systems (mammalian cell culture, yeast, Drosophila, in vitro reconstituted systems), and the broad range of approaches employed (ultrastructural, biophysical, biochemical, genetic, ..). At the heart of the Program is a state-of-the-art light microscopy core facility, which allows researchers to analyse in vivo the dynamics and interactions of biomolecules in their natural cellular context.
Research groups in the Cell biology Program:
- Macromolecular Complexes in Live Cells (Maïté Coppey)
- Nuclear Pores: Transport and Cell Cycle (Valérie Doye)
- Cell Division and Reproduction (Julien Dumont)
- Ubiquitin and Trafficking (Rosine Haguenauer-Tsapis)
- Membrane Dynamics and Intracellular Trafficking (Cathy Jackson)
- Molecular Virology (Isabelle Jupin)
- Regulation and Dynamics of Cell Division (Roger Karess)
- Development, signalisation and traffic (Anne Plessis)
- Membrane Dynamics and Regulation (Anne Schmidt)
See the Organizational Chart of the Institut Jacques-Monod.
Last modified 11/ 8/2011