Imaging

The core facility Imaging at the Institut Jacques-Monod has been assessed and found to meet the requirements of ISO 9001 by AFNOR Certification. The certificate is valid from 2009-12-30 until 2012-12-29.

This Imaging facility is part of the National Imaging Facilities Centers network (RIO).

It is open to all members of the scientific community - both academic and privately-funded.

Missions

  • to offer biologists state-of-the art photonic microscopy together with expertise in luminescence and image processing;
  • to promote dissemination of technical and scientific knowledge through the organisation of national and international networks, seminars and courses; 
  • to encourage the interest and involvement of medical laboratories and industries that wish to characterise and control the molecular and nanoscale properties of biological material in living cells.


Scientific activities
The Imaging facility specialises in the visualisation and  analysis by photonic microscopy of dynamic processes in cells (prokaryotic and eukaryotic) and in living organisms (embryos of small animals, e.g. Drosophila, C. elegans, Xenopus, fish and mouse) .

The Imaging facility develops techniques that present the following features:

  • minimal invasiveness
  • high spatial resolution (subcellular resolution in embryos)
  • temporal resolutions adapted to the observation of dynamic processes in real time, e.g. from ~ 50 ms for dynamics of macromolecules up to several hours or days for cell migration within embryos
  • high information content: multiparametric and quantitative observations,  imaging of macromolecular interactions, biochemical reactions, ion fluxes, membrane fusion,....
  • nano- and photomanipulation (photobleaching, photoactivation, photoablation,..)
  • image processing and analysis

Scientific supervisors:
Maïté Coppey-Moisan, Aude Jobart-Malfait
Building Buffon, tel: 33 (0)1 57 27 81 54

Last modified 04/13/2011

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